pentobarbital will lessen the level or effect of cevimeline by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.

pentobarbital will lower the extent or impact of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Use of naloxegol with potent CYP3A4 inducers is just not advised

pentobarbital will lessen the level or result of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Importance Mysterious.

Monitor Carefully (1)pentobarbital will minimize the level or impact of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

Contraindicated (one)pentobarbital will lower the extent or result of doravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will reduce the level or impact of vinblastine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.

pentobarbital will decrease the extent or effect of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Robust CYP3A4 inducers may perhaps lessen suvorexant efficacy; if elevated suvorexant dose demanded, tend not to exceed twenty mg/day

pentobarbital will reduce the level or outcome of atorvastatin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital will lower the level or result of clozapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Contraindications to pentobarbital use consist of prior hypersensitivity reactions to drug use or barbiturate course use. Barbiturates can induce hypersensitivity reactions by direct histamine launch or immunoglobulin E (IgE)–mediated here mechanisms and can cause anaphylaxis.

lasmiditan, pentobarbital. Both raises effects of one other by sedation. Use Warning/Check. Coadministration of lasmiditan and also other CNS depressant medications, which includes alcohol haven't been evaluated in scientific scientific tests. Lasmiditan may possibly result in sedation, in addition to other cognitive and/or neuropsychiatric adverse reactions.

fentanyl transdermal and pentobarbital both equally raise sedation. Steer clear of or Use Alternate Drug. Restrict use to sufferers for whom substitute therapy possibilities are insufficient

pentobarbital will lessen the extent or impact of alosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known.

pentobarbital will lower the level or result of diclofenac by impacting hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Unfamiliar.